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Biomarker Intelligence Platform

Find the biomarkers
that matter

Motif turns literature into structured, cross-referenced, cited biomarker associations.

The biomarker that changes your research may already be published. Motif finds it.

Limited early access for researchers. No spam.

Search papers

CAR-T resistance biomarkers solid tumor
Epigenetic Barriers to CAR-T Persistence in Solid Tumors
TIL Exhaustion and PD-1 in NSCLC Microenvironment
CTLA-4 Upregulation in Adoptive Cell Therapy Failure
CD8+ T Cell Dysfunction Across Solid Tumor Types
Biomarkers of Non-Response to CAR-T in Pancreatic Cancer

Collect relevant papers

Relevance screening3 accepted / 2 rejected
Epigenetic Barriers to CAR-T Persistence in Solid TumorsACCEPT
TIL Exhaustion and PD-1 in NSCLC MicroenvironmentACCEPT
CTLA-4 Upregulation in Adoptive Cell Therapy FailureACCEPT
CD8+ T Cell Dysfunction Across Solid Tumor TypesREJECT
Biomarkers of Non-Response to CAR-T in Pancreatic CancerREJECT

Extract biomarker associations

Generate report

ACTION REPORT1Summary2Evidence3ActionsLITERATURE REVIEW1Background2Key themes3ConclusionGRANT PROPOSAL1Project aims2Significance3Approach

Generate knowledge graph

Knowledge graph

Biomarker relationships extracted from a single paper

CAR-T resistanceT cell exhaustionCTLA-4PD-1TILsEpigenetic barrier scoreCD8+ T cells

How it works

Not a summary.
Your biomarker graph,
built as you go.

Each paper extends your biomarker graph as you work. Every association is PMID-linked and cross-referenced across 50+ databases—nothing synthetic, only what the literature says.

Interactive knowledge graph

See relationships no spreadsheet can show

An interactive network of biomarker associations. Filter by disease, evidence strength, or relationship type. Export to Cytoscape, PDF, Excel, or SVG.

  • Filter nodes by biomedical entity type, evidence class, or disease area
  • Explore any node to expand its sub-graph
  • Export as PDF, XLSX, CSV, SVG, or Cytoscape for figures and downstream analysis

No black-box synthesis

Associations you can inspect, trust, and cite

Every result maps a biomarker to disease, drug, or phenotype with full provenance: direct quotes from the source text or interpretations extracted from figures. No synthesis you have to take on faith.

  • Relationship type, direction, and confidence surfaced per result
  • Supporting evidence as verbatim quotes or figure interpretations
  • Raw PMID links for every association
  • Export-ready for grants, slides, or literature tables

Example Association Library output showing three biomarker associations: EGFR exon 19 deletion associated with improved progression-free survival on osimertinib (High confidence), BRCA2 loss-of-function associated with reduced overall survival in pancreatic cancer (Moderate confidence), and PTEN loss associated with PI3K pathway activation (Low confidence).

Example Article Library showing 25 total articles with extraction status badges. Articles include titles, authors, journal, year, PMID, and DOI with findings count badges, and actions to view, copy title, add supplementary files, or archive.

All your sources, one place

A library that keeps itself organized

Every paper Motif reads is stored with its full citation, DOI, and journal. Complete provenance for every finding, searchable and exportable without leaving the platform.

  • Search across all papers by title, author, or journal
  • Export your library as BibTeX or RIS for any reference manager
  • Every source DOI-linked, no broken references

Built for teams

Collaborate on the same knowledge graph

Your team works in the same graph. Add notes to any node or association, tag context, and surface what matters without duplicating the review work.

  • Annotate any node or association with team notes
  • Tag context to keep findings organised by project or hypothesis
  • Everyone sees the same evidence, no version drift

Example Team Notes panel showing collaborative annotation on an EGFR association, with a team note in progress reading: Consistent with FLAURA data, prioritise for osimertinib arm.

Beyond PubMed and spreadsheets

PubMed gives you papers.
Motif gives you biomarker evidence.

Weeks of reading, one query

Structured biomarker associations with full provenance. The manual literature work your team used to spread across weeks, in a single search. No sales calls, no procurement team.

Compounding your team's knowledge

Every query adds to your organization's biomarker graph. What used to take years of accumulated reading becomes searchable in days, and every search after that starts from where your team left off.

Evidence you can trust

Each result is scored by study design, sample size, and effect size. You see how much to trust a finding before you cite it.

Who Motif Is For

Built for teams
who turn literature into decisions.

Precision Medicine Researchers

Find resistance and response biomarkers from the literature before you commit wet-lab resources.

Translational Scientists

Prioritize biomarker candidates with cited diagnostic, prognostic, and predictive associations in one place.

Companion Diagnostic Teams

Map biomarker-treatment relationships with cited evidence and certainty scores for assay and trial design.

Early access

Start building your biomarker graph.

Join the waitlist for early access to the Biomarker Intelligence Platform.

Find the biomarkers that matter - Motif